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Developing Targeted Therapeutics in Angelman SyndromeThe genomic revolution has led to increasing opportunities to address complex neurodevelopmental conditions, taking a genetics-first approach.
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New Treatment for Rare Autoimmune DiseaseA new treatment for NMOSD has been found to reduce relapse, decrease re-hospitalizations, and hinder the need to treat acute attacks with corticosteroids and plasma exchange.
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Prion-like Molecular Mechanisms in Alzheimer DiseaseAlthough Alzheimer disease is not infectious by any common definition of the term, research over the past 20 years has confirmed long-standing speculation that the molecular mechanism driving neurodegeneration is fundamentally the same in Alzheimer disease and the prototypical infectious proteopathy-prion disease.
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Understanding the Impact of Data Analysis on Preventive Migraine Treatment: Jessica Ailani, MDThe director of the MedStar Georgetown Headache Center discussed the importance of maintaining hope and providing understanding of patients' frustrations in their treatment journey for migraine. [WATCH TIME: 5 minutes]
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FibroGen's Duchenne Muscular Dystrophy Antibody Pamrevlumab Falls Short in Phase 3The study did not meet its primary end point of change from baseline in Performance of the Upper Limb 2.0 score at 1 year.
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FDA Rejects Duchenne Muscular Dystrophy Drug Golodirsen, Citing Safety ConcernsThe regulatory agency cited 2 concerns in the complete response letter: the risk of infections related to intravenous infusion ports and renal toxicity.
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Unusual New Onset Seizures in a Healthy, Young Adult MaleA 23-year-old male college student presents with first generalized tonic-clonic seizure followed by episodes of violent psychosis.
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NeurologyLive® Brain Games: January 21, 2024Test your neurology knowledge with NeurologyLive®'s weekly quiz series, featuring questions on a variety of clinical and historical neurology topics. This week's topic is headache and migraine.
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Using the Ketogenic Diet to Treat Intractable Epilepsy in Case of Glycine EncephalopathyA boy diagnosed with glycine encephalopathy in the newborn period was initiated on the ketogenic diet at 11 years-old for the treatment of medication refractory epilepsy.
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Understanding Cerebral Venous Thrombosis: Rare But Sometimes FatalThe prognosis of cerebral venous thrombosis (CVT) is favorable compared with other types of stroke: almost 80% of patients with CVT recover without functional disability. Nevertheless, 5% to 10% of patients die in the acute phase.
Latest:
Understanding Cerebral Venous Thrombosis: Rare But Sometimes FatalThe prognosis of cerebral venous thrombosis (CVT) is favorable compared with other types of stroke: almost 80% of patients with CVT recover without functional disability. Nevertheless, 5% to 10% of patients die in the acute phase.
Latest:
Understanding Cerebral Venous Thrombosis: Rare But Sometimes FatalThe prognosis of cerebral venous thrombosis (CVT) is favorable compared with other types of stroke: almost 80% of patients with CVT recover without functional disability. Nevertheless, 5% to 10% of patients die in the acute phase.
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Case Report: New Onset Paroxysmal Episodes in an InfantA newborn presents with new onset episodes of lateral gaze deviation with extremity stiffening.
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Closing the Treatment Gap in Progressive MSNew biomarkers of disease activity may help better vet investigational therapies aimed at slowing the insidious neurodegeneration seen in primary progressive multiple sclerosis.
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Introducing DaxibotulinumtoxinA-Ianm as a Treatment Option for Cervical Dystonia: Peter J. McAllister, MD, FAANThe chief medical officer of New England Center for Neurology and Headache talked about trends observed in the clinical practice with Daxxify, a long-acting botulinum toxin for patients with cervical dystonia. [WATCH TIME: 5 minutes]
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Cyclic Vomiting, Incontinence in a Young BoyAn 8 year old boy with genetically confirmed neurofibromatosis type 1 presents with first generalized seizure.
